SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01443

Signal sequence   IPLVANVSFNSDNGSQWLYREEE

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01443.cif

Structure  SPKB01443.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2667.87114

Aliphatic index  80.43478261

Isoelectric point  3.778239002

Charge (pH=7)   -2.997097574

Topological polar surface area  1174.9

Aromaticity  0.130434783

Average rotatable bonds  3.695652174

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  37

X logP energy  -12.21233

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.