SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01401

Signal sequence   IPLVANVSFNSDNGSQWLYKGP

Length  22

Organism  Artificial

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01401.cif

Structure  SPKB01401.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2406.67984

Aliphatic index  84.09090909

Isoelectric point  6.330585692

Charge (pH=7)   -0.002714665

Topological polar surface area  989.23

Aromaticity  0.136363636

Average rotatable bonds  3.318181818

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -10.2882

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.