SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01399

Signal sequence   IPLVANVSFNSDNGSQWLYKEK

Length  22

Organism  Artificial

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01399.cif

Structure  SPKB01399.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2509.80084

Aliphatic index  84.09090909

Isoelectric point  6.486213354

Charge (pH=7)   -0.001234576

Topological polar surface area  1061.34

Aromaticity  0.136363636

Average rotatable bonds  3.681818182

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  35

X logP energy  -10.432

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.