SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01376

Signal sequence   IPLVANVSFNSDNGSQWLYKE

Length  21

Organism  Artificial

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01376.cif

Structure  SPKB01376.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2381.62674

Aliphatic index  88.0952381

Isoelectric point  4.184406685

Charge (pH=7)   -1.000939542

Topological polar surface area  1006.22

Aromaticity  0.142857143

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  33

X logP energy  -10.0458

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.