SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01373

Signal sequence   IPLVANVSFNSDNGSQWLYG

Length  20

Organism  Artificial

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01373.cif

Structure  SPKB01373.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2181.38904

Aliphatic index  92.5

Isoelectric point  3.749986963

Charge (pH=7)   -1.002419631

Topological polar surface area  913.8

Aromaticity  0.15

Average rotatable bonds  3.3

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  30

X logP energy  -9.893

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.