SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01371

Signal sequence   IPLVANVSFNSDNGSQWLYR

Length  20

Organism  Artificial

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01371.cif

Structure  SPKB01371.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2280.52464

Aliphatic index  92.5

Isoelectric point  6.331895378

Charge (pH=7)   -0.002422942

Topological polar surface area  975.7

Aromaticity  0.15

Average rotatable bonds  3.5

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  31

X logP energy  -10.26113

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.