SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01364

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAKREEEPK

Length  49

Organism  Artificial

UniProt ID  NA,

Motif  1..49



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01364.cif

Structure  SPKB01364.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5228.65364

Aliphatic index  65.71428571

Isoelectric point  3.71492417

Charge (pH=7)   -6.991501045

Topological polar surface area  2367.46

Aromaticity  0.020408163

Average rotatable bonds  3.612244898

Number of hydrogen bond donors  79

Number of hydrogen bond acceptors  81

X logP energy  -32.38533

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.