SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01358

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAREEEPK

Length  48

Organism  Artificial

UniProt ID  NA,

Motif  1..48



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01358.cif

Structure  SPKB01358.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5100.47954

Aliphatic index  67.08333333

Isoelectric point  3.526882561

Charge (pH=7)   -7.991206011

Topological polar surface area  2312.34

Aromaticity  0.020833333

Average rotatable bonds  3.5625

Number of hydrogen bond donors  77

Number of hydrogen bond acceptors  79

X logP energy  -31.99913

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.