SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01353

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAKEEGPK

Length  48

Organism  Artificial

UniProt ID  NA,

Motif  1..48



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01353.cif

Structure  SPKB01353.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5000.40254

Aliphatic index  67.08333333

Isoelectric point  3.572633006

Charge (pH=7)   -6.993272857

Topological polar surface area  2239.16

Aromaticity  0.020833333

Average rotatable bonds  3.5

Number of hydrogen bond donors  74

Number of hydrogen bond acceptors  78

X logP energy  -31.3668

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.