SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01345

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAKREEPK

Length  48

Organism  Artificial

UniProt ID  NA,

Motif  1..48



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01345.cif

Structure  SPKB01345.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5099.53814

Aliphatic index  67.08333333

Isoelectric point  3.770008237

Charge (pH=7)   -5.993276168

Topological polar surface area  2301.06

Aromaticity  0.020833333

Average rotatable bonds  3.583333333

Number of hydrogen bond donors  77

Number of hydrogen bond acceptors  79

X logP energy  -31.73493

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.