SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01340

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAKREEGE

Length  48

Organism  Artificial

UniProt ID  NA,

Motif  1..48



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01340.cif

Structure  SPKB01340.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5060.41474

Aliphatic index  67.08333333

Isoelectric point  3.526882561

Charge (pH=7)   -7.991206011

Topological polar surface area  2321.13

Aromaticity  0.020833333

Average rotatable bonds  3.583333333

Number of hydrogen bond donors  78

Number of hydrogen bond acceptors  79

X logP energy  -32.87393

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.