SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01336

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAEEGEK

Length  47

Organism  Artificial

UniProt ID  NA,

Motif  1..47



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01336.cif

Structure  SPKB01336.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4904.22724

Aliphatic index  68.5106383

Isoelectric point  3.294141002

Charge (pH=7)   -8.9912027

Topological polar surface area  2230.13

Aromaticity  0.021276596

Average rotatable bonds  3.531914894

Number of hydrogen bond donors  74

Number of hydrogen bond acceptors  77

X logP energy  -31.622

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.