SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01328

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAREEEP

Length  47

Organism  Artificial

UniProt ID  NA,

Motif  1..47



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01328.cif

Structure  SPKB01328.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4972.30544

Aliphatic index  68.5106383

Isoelectric point  3.294141015

Charge (pH=7)   -8.990910977

Topological polar surface area  2257.22

Aromaticity  0.021276596

Average rotatable bonds  3.510638298

Number of hydrogen bond donors  75

Number of hydrogen bond acceptors  77

X logP energy  -31.61293

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.