SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01320

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAKEEGK

Length  47

Organism  Artificial

UniProt ID  NA,

Motif  1..47



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01320.cif

Structure  SPKB01320.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4903.28584

Aliphatic index  68.5106383

Isoelectric point  3.572633006

Charge (pH=7)   -6.993272857

Topological polar surface area  2218.85

Aromaticity  0.021276596

Average rotatable bonds  3.553191489

Number of hydrogen bond donors  74

Number of hydrogen bond acceptors  77

X logP energy  -31.3578

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.