SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01307

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAKREEK

Length  47

Organism  Artificial

UniProt ID  NA,

Motif  1..47



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01307.cif

Structure  SPKB01307.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5002.42144

Aliphatic index  68.5106383

Isoelectric point  3.770008237

Charge (pH=7)   -5.993276168

Topological polar surface area  2280.75

Aromaticity  0.021276596

Average rotatable bonds  3.638297872

Number of hydrogen bond donors  77

Number of hydrogen bond acceptors  78

X logP energy  -31.72593

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.