SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01297

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAEEEP

Length  46

Organism  Artificial

UniProt ID  NA,

Motif  1..46



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01297.cif

Structure  SPKB01297.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4816.11794

Aliphatic index  70

Isoelectric point  2.941402606

Charge (pH=7)   -9.990907666

Topological polar surface area  2166.22

Aromaticity  0.02173913

Average rotatable bonds  3.456521739

Number of hydrogen bond donors  71

Number of hydrogen bond acceptors  75

X logP energy  -30.361

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.