SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01276

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAKEEE

Length  46

Organism  Artificial

UniProt ID  NA,

Motif  1..46



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01276.cif

Structure  SPKB01276.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4847.17534

Aliphatic index  70

Isoelectric point  3.294141002

Charge (pH=7)   -8.9912027

Topological polar surface area  2201.03

Aromaticity  0.02173913

Average rotatable bonds  3.565217391

Number of hydrogen bond donors  73

Number of hydrogen bond acceptors  76

X logP energy  -30.7382

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.