SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01270

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAKRGK

Length  46

Organism  Artificial

UniProt ID  NA,

Motif  1..46



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01270.cif

Structure  SPKB01270.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4801.24234

Aliphatic index  70

Isoelectric point  3.913407609

Charge (pH=7)   -3.996826413

Topological polar surface area  2177.05

Aromaticity  0.02173913

Average rotatable bonds  3.543478261

Number of hydrogen bond donors  74

Number of hydrogen bond acceptors  75

X logP energy  -31.30893

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.