SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01264

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAKREE

Length  46

Organism  Artificial

UniProt ID  NA,

Motif  1..46



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01264.cif

Structure  SPKB01264.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4874.24734

Aliphatic index  70

Isoelectric point  3.572633019

Charge (pH=7)   -6.992981134

Topological polar surface area  2225.63

Aromaticity  0.02173913

Average rotatable bonds  3.586956522

Number of hydrogen bond donors  75

Number of hydrogen bond acceptors  76

X logP energy  -31.33973

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.