SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01256

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAEEK

Length  45

Organism  Artificial

UniProt ID  NA,

Motif  1..45



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01256.cif

Structure  SPKB01256.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4718.05984

Aliphatic index  71.55555556

Isoelectric point  3.332655265

Charge (pH=7)   -7.992977823

Topological polar surface area  2134.63

Aromaticity  0.022222222

Average rotatable bonds  3.533333333

Number of hydrogen bond donors  71

Number of hydrogen bond acceptors  74

X logP energy  -30.0878

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.