SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01255

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAEEP

Length  45

Organism  Artificial

UniProt ID  NA,

Motif  1..45



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01255.cif

Structure  SPKB01255.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4687.00244

Aliphatic index  71.55555556

Isoelectric point  2.974098442

Charge (pH=7)   -8.992682789

Topological polar surface area  2099.82

Aromaticity  0.022222222

Average rotatable bonds  3.422222222

Number of hydrogen bond donors  69

Number of hydrogen bond acceptors  73

X logP energy  -29.7106

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.