SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01250

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMARGP

Length  45

Organism  Artificial

UniProt ID  NA,

Motif  1..45



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01250.cif

Structure  SPKB01250.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4642.01084

Aliphatic index  71.55555556

Isoelectric point  3.423773605

Charge (pH=7)   -5.996236346

Topological polar surface area  2087.12

Aromaticity  0.022222222

Average rotatable bonds  3.377777778

Number of hydrogen bond donors  70

Number of hydrogen bond acceptors  72

X logP energy  -30.54553

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.