SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01230

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAGP

Length  44

Organism  Artificial

UniProt ID  NA,

Motif  1..44



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01230.cif

Structure  SPKB01230.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4485.82334

Aliphatic index  73.18181818

Isoelectric point  3.048797385

Charge (pH=7)   -6.996233034

Topological polar surface area  1996.12

Aromaticity  0.022727273

Average rotatable bonds  3.318181818

Number of hydrogen bond donors  66

Number of hydrogen bond acceptors  70

X logP energy  -29.2936

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.