SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01218

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAKG

Length  44

Organism  Artificial

UniProt ID  NA,

Motif  1..44



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01218.cif

Structure  SPKB01218.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4516.88074

Aliphatic index  73.18181818

Isoelectric point  3.423773592

Charge (pH=7)   -5.996528068

Topological polar surface area  2030.93

Aromaticity  0.022727273

Average rotatable bonds  3.431818182

Number of hydrogen bond donors  68

Number of hydrogen bond acceptors  71

X logP energy  -29.6708

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.