SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01214

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAG

Length  43

Organism  Artificial

UniProt ID  NA,

Motif  1..43



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01214.cif

Structure  SPKB01214.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4388.70664

Aliphatic index  74.88372093

Isoelectric point  3.048797385

Charge (pH=7)   -6.996233034

Topological polar surface area  1975.81

Aromaticity  0.023255814

Average rotatable bonds  3.372093023

Number of hydrogen bond donors  66

Number of hydrogen bond acceptors  69

X logP energy  -29.2846

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.