SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01212

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMAR

Length  43

Organism  Artificial

UniProt ID  NA,

Motif  1..43



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01212.cif

Structure  SPKB01212.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4487.84224

Aliphatic index  74.88372093

Isoelectric point  3.423773605

Charge (pH=7)   -5.996236346

Topological polar surface area  2037.71

Aromaticity  0.023255814

Average rotatable bonds  3.465116279

Number of hydrogen bond donors  69

Number of hydrogen bond acceptors  70

X logP energy  -29.65273

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.