SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01210

Signal sequence   QPIDDTESQTTSVNLMADDTESAFATQTNSGGLDVVGLISMA

Length  42

Organism  Artificial

UniProt ID  NA,

Motif  1..42



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01210.cif

Structure  SPKB01210.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4331.65474

Aliphatic index  76.66666667

Isoelectric point  3.048797385

Charge (pH=7)   -6.996233034

Topological polar surface area  1946.71

Aromaticity  0.023809524

Average rotatable bonds  3.404761905

Number of hydrogen bond donors  65

Number of hydrogen bond acceptors  68

X logP energy  -28.4008

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.