SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01209

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDKREEGEPK

Length  77

Organism  Artificial

UniProt ID  NA,

Motif  1..77



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01209.cif

Structure  SPKB01209.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  8049.79694

Aliphatic index  92.5974026

Isoelectric point  3.65683865

Charge (pH=7)   -10.98377088

Topological polar surface area  3480.98

Aromaticity  0.038961039

Average rotatable bonds  3.454545455

Number of hydrogen bond donors  115

Number of hydrogen bond acceptors  117

X logP energy  -41.17553

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.