SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01203

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDKREEGPK

Length  76

Organism  Artificial

UniProt ID  NA,

Motif  1..76



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01203.cif

Structure  SPKB01203.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7920.68144

Aliphatic index  93.81578947

Isoelectric point  3.692750935

Charge (pH=7)   -9.985546002

Topological polar surface area  3414.58

Aromaticity  0.039473684

Average rotatable bonds  3.434210526

Number of hydrogen bond donors  113

Number of hydrogen bond acceptors  115

X logP energy  -40.52513

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.