SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01202

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDKREEGEK

Length  76

Organism  Artificial

UniProt ID  NA,

Motif  1..76



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01202.cif

Structure  SPKB01202.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7952.68024

Aliphatic index  93.81578947

Isoelectric point  3.65683865

Charge (pH=7)   -10.98377088

Topological polar surface area  3460.67

Aromaticity  0.039473684

Average rotatable bonds  3.486842105

Number of hydrogen bond donors  115

Number of hydrogen bond acceptors  116

X logP energy  -41.16653

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.