SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01193

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDEEGEPK

Length  75

Organism  Artificial

UniProt ID  NA,

Motif  1..75



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01193.cif

Structure  SPKB01193.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7765.43534

Aliphatic index  95.06666667

Isoelectric point  3.355642469

Charge (pH=7)   -12.98347253

Topological polar surface area  3334.86

Aromaticity  0.04

Average rotatable bonds  3.386666667

Number of hydrogen bond donors  109

Number of hydrogen bond acceptors  113

X logP energy  -39.5374

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.