SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01176

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDKREEEP

Length  75

Organism  Artificial

UniProt ID  NA,

Motif  1..75



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01176.cif

Structure  SPKB01176.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7864.57094

Aliphatic index  95.06666667

Isoelectric point  3.518861149

Charge (pH=7)   -11.98347585

Topological polar surface area  3396.76

Aromaticity  0.04

Average rotatable bonds  3.44

Number of hydrogen bond donors  112

Number of hydrogen bond acceptors  114

X logP energy  -39.90553

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.