SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01131

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDKEEEK

Length  74

Organism  Artificial

UniProt ID  NA,

Motif  1..74



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01131.cif

Structure  SPKB01131.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7739.44084

Aliphatic index  96.35135135

Isoelectric point  3.518861142

Charge (pH=7)   -11.98376757

Topological polar surface area  3340.57

Aromaticity  0.040540541

Average rotatable bonds  3.472972973

Number of hydrogen bond donors  110

Number of hydrogen bond acceptors  113

X logP energy  -39.0308

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.