SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01126

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDKRGPK

Length  74

Organism  Artificial

UniProt ID  NA,

Motif  1..74



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01126.cif

Structure  SPKB01126.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7662.45044

Aliphatic index  96.35135135

Isoelectric point  3.776396647

Charge (pH=7)   -7.989096248

Topological polar surface area  3281.78

Aromaticity  0.040540541

Average rotatable bonds  3.391891892

Number of hydrogen bond donors  109

Number of hydrogen bond acceptors  111

X logP energy  -39.22433

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.