SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01115

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLEGEPK

Length  73

Organism  Artificial

UniProt ID  NA,

Motif  1..73



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01115.cif

Structure  SPKB01115.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7521.23124

Aliphatic index  97.67123288

Isoelectric point  3.429816585

Charge (pH=7)   -10.98569414

Topological polar surface area  3202.06

Aromaticity  0.04109589

Average rotatable bonds  3.356164384

Number of hydrogen bond donors  105

Number of hydrogen bond acceptors  109

X logP energy  -37.8465

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.