SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01100

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLKGEPK

Length  73

Organism  Artificial

UniProt ID  NA,

Motif  1..73



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01100.cif

Structure  SPKB01100.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7520.28984

Aliphatic index  97.67123288

Isoelectric point  3.639786116

Charge (pH=7)   -8.987764298

Topological polar surface area  3190.78

Aromaticity  0.04109589

Average rotatable bonds  3.369863014

Number of hydrogen bond donors  105

Number of hydrogen bond acceptors  109

X logP energy  -37.5823

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.