SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01083

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLKREEK

Length  73

Organism  Artificial

UniProt ID  NA,

Motif  1..73



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01083.cif

Structure  SPKB01083.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7651.42424

Aliphatic index  97.67123288

Isoelectric point  3.746894096

Charge (pH=7)   -8.985992486

Topological polar surface area  3298.77

Aromaticity  0.04109589

Average rotatable bonds  3.479452055

Number of hydrogen bond donors  110

Number of hydrogen bond acceptors  111

X logP energy  -38.59183

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.