SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01081

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLKREEE

Length  73

Organism  Artificial

UniProt ID  NA,

Motif  1..73



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01081.cif

Structure  SPKB01081.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7652.36564

Aliphatic index  97.67123288

Isoelectric point  3.56452539

Charge (pH=7)   -10.98392233

Topological polar surface area  3310.05

Aromaticity  0.04109589

Average rotatable bonds  3.465753425

Number of hydrogen bond donors  110

Number of hydrogen bond acceptors  111

X logP energy  -38.85603

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.