SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01066

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDREPK

Length  73

Organism  Artificial

UniProt ID  NA,

Motif  1..73



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01066.cif

Structure  SPKB01066.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7606.33994

Aliphatic index  97.67123288

Isoelectric point  3.585852047

Charge (pH=7)   -9.987026091

Topological polar surface area  3263.96

Aromaticity  0.04109589

Average rotatable bonds  3.397260274

Number of hydrogen bond donors  108

Number of hydrogen bond acceptors  110

X logP energy  -38.60473

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.