SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB01028

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLRGEK

Length  72

Organism  Artificial

UniProt ID  NA,

Motif  1..72



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB01028.cif

Structure  SPKB01028.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7451.18654

Aliphatic index  99.02777778

Isoelectric point  3.639786123

Charge (pH=7)   -8.987472575

Topological polar surface area  3206.35

Aromaticity  0.041666667

Average rotatable bonds  3.402777778

Number of hydrogen bond donors  107

Number of hydrogen bond acceptors  108

X logP energy  -38.43903

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.