SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00955

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLRGP

Length  71

Organism  Artificial

UniProt ID  NA,

Motif  1..71



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00955.cif

Structure  SPKB00955.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7291.01364

Aliphatic index  100.4225352

Isoelectric point  3.502579589

Charge (pH=7)   -8.988952664

Topological polar surface area  3105.14

Aromaticity  0.042253521

Average rotatable bonds  3.309859155

Number of hydrogen bond donors  103

Number of hydrogen bond acceptors  105

X logP energy  -37.41143

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.