SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00922

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLDKE

Length  71

Organism  Artificial

UniProt ID  NA,

Motif  1..71



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00922.cif

Structure  SPKB00922.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7353.03574

Aliphatic index  100.4225352

Isoelectric point  3.415448245

Charge (pH=7)   -10.98702278

Topological polar surface area  3152.65

Aromaticity  0.042253521

Average rotatable bonds  3.394366197

Number of hydrogen bond donors  104

Number of hydrogen bond acceptors  107

X logP energy  -37.3438

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.