SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00916

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLEK

Length  70

Organism  Artificial

UniProt ID  NA,

Motif  1..70



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00916.cif

Structure  SPKB00916.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7237.94714

Aliphatic index  101.8571429

Isoelectric point  3.464513126

Charge (pH=7)   -9.987469264

Topological polar surface area  3086.25

Aromaticity  0.042857143

Average rotatable bonds  3.385714286

Number of hydrogen bond donors  102

Number of hydrogen bond acceptors  105

X logP energy  -36.3033

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.