SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00897

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLG

Length  69

Organism  Artificial

UniProt ID  NA,

Motif  1..69



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00897.cif

Structure  SPKB00897.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7037.70944

Aliphatic index  103.3333333

Isoelectric point  3.275274953

Charge (pH=7)   -9.988949353

Topological polar surface area  2993.83

Aromaticity  0.043478261

Average rotatable bonds  3.304347826

Number of hydrogen bond donors  99

Number of hydrogen bond acceptors  102

X logP energy  -36.1505

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.