SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00895

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLR

Length  69

Organism  Artificial

UniProt ID  NA,

Motif  1..69



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00895.cif

Structure  SPKB00895.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7136.84504

Aliphatic index  103.3333333

Isoelectric point  3.502579589

Charge (pH=7)   -8.988952664

Topological polar surface area  3055.73

Aromaticity  0.043478261

Average rotatable bonds  3.362318841

Number of hydrogen bond donors  102

Number of hydrogen bond acceptors  103

X logP energy  -36.51863

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.