SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00893

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSLD

Length  69

Organism  Artificial

UniProt ID  NA,

Motif  1..69



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00893.cif

Structure  SPKB00893.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  7095.74614

Aliphatic index  103.3333333

Isoelectric point  3.22693276

Charge (pH=7)   -10.98850287

Topological polar surface area  3031.13

Aromaticity  0.043478261

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  100

Number of hydrogen bond acceptors  103

X logP energy  -36.3072

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.