SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00892

Signal sequence   SLALAAPVNTTTEDETAQIPAEAVIGYSDLEGDEDVAVLPFSNSTNNGLLFINTTIASIAAKEEGVSL

Length  68

Organism  Artificial

UniProt ID  NA,

Motif  1..68



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00892.cif

Structure  SPKB00892.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6980.65754

Aliphatic index  104.8529412

Isoelectric point  3.275274953

Charge (pH=7)   -9.988949353

Topological polar surface area  2964.73

Aromaticity  0.044117647

Average rotatable bonds  3.323529412

Number of hydrogen bond donors  98

Number of hydrogen bond acceptors  101

X logP energy  -35.2667

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.