SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00880

Signal sequence   MKLSSLLLALLLALASLALA

Length  20

Organism  Artificial

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00880.cif

Structure  SPKB00880.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2025.60454

Aliphatic index  220

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  702.93

Aromaticity  0

Average rotatable bonds  3.45

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -1.971

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.