SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00874

Signal sequence   MKLLLLLLLLLLLLLLLALVLA

Length  22

Organism  Artificial

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00874.cif

Structure  SPKB00874.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2442.38194

Aliphatic index  323.6363636

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  700.44

Aromaticity  0

Average rotatable bonds  3.863636364

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  7.9407

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.