SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00868

Signal sequence   MFSPILSLEIILALATLQSVFAR

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00868.cif

Structure  SPKB00868.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2534.09534

Aliphatic index  161.3043478

Isoelectric point  6.410149741

Charge (pH=7)   -0.000243889

Topological polar surface area  917.94

Aromaticity  0.086956522

Average rotatable bonds  3.565217391

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  32

X logP energy  -4.35563

Hydropathy 



Literature Information


Title  SYNTHETIC SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN YEAST

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240174722A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.